دواء جاوتيفيد Goutifade لعلاج النقرص, املاح اليوريك

Price, dosage, and directions for use of Gautivide Goutifade For the treatment of gout to “reduce uric salts”.

What is the medicine Gautived?

• Gautivid contains the active ingredient “febuxostat”, which belongs to the group of “xanthine oxidative enzyme inhibitors”.
• Febuxostat helps treat gout, where gout is associated with an excess of a chemical called uric acid (urate) in the body. Urate crystals form in and around the joints and kidneys and these crystals can cause sudden severe pain, redness, warmth and swelling in the joints (known as a gout attack). It results in joint and bone damage.
• Gautivide works by lowering uric acid levels to keep uric acid levels low by taking Gautivide once each day to stop the crystals building up. Over time, it reduces symptoms. Keeping uric acid levels low enough for a long time can also diminish (deceased).
• Gautived is also used to treat and prevent the increase in uric acid in the blood, which may appear when starting to receive chemotherapy, for cancers of the blood, when receiving chemotherapy, the destruction of cancer cells occurs, which leads to an increase in uric acid in the blood, unless the formation of Uric acid.

What are the indications for the use of the drug Gautivid?

Gautived is used to treat the following conditions:

• Gout treatment.
• To prevent gout attacks.
• For the treatment and prevention of high levels of uric acid in the body of patients taking chemotherapy for cancer.

Pharmaceutical form and components of Gautivide:

• febuxostat ( Febuxostat ).
• Coated tablets are available in concentrations: (40 mg – 80 mg – 120 mg).

Guttifed Dosage and Instructions:

• This medication should be taken exactly as prescribed by your doctor, see your doctor or pharmacist if you are not sure.
• GUTIFID is available in either 40 mg, 80 mg or 120 mg concentrations. Your doctor will prescribe the appropriate concentration for you.
• Gout treatment dose: The usual dose for treating gout is one tablet per day (concentration as directed by your doctor).
• The tablet should be taken with or without food.
• Continue to take Gautivide every day, even when you don’t have a gout attack. (as per doctor’s instructions)
• If you take more Gutivid than you should (an overdose), tell your doctor what to do or call your nearest emergency department.
• If you forget to take a dose of Gautivide, take it as soon as you remember unless it is close to the time for your next dose, in which case do not take the forgotten dose and take the next dose at the regular time. Do not take a double dose to make up for a forgotten dose.
• Even if you feel better, do not stop taking GUTIFID before talking to your doctor. If you stop taking this medicine your uric acid levels may start to rise and your symptoms may get worse due to the formation of new urate crystals in and around your joints and kidneys.

Contraindications to the use of Gautivide:

• Do not take Gautivide if you are allergic to febuxostat (the active ingredient) or any of the other ingredients of the medicine.
• This medicine should not be used in children under 18 years of age, as the safety and efficacy of the medicine have not yet been confirmed.
• Gautivide contains lactose (a type of sugar). If you have been told before that you are unable to accept some sugars, consult your doctor before taking this medicine.

Warnings and precautions for use:

Consult your doctor before you start taking this medicine if you have:

• If you have or have had heart problems.
• if you have or have ever had kidney problems and/or a severe allergy to allopurinol (a medicine used to treat gout)
• If you have and have had liver problems or a defect in the selection of liver functions.
• If you are being treated for high levels of uric acid as a result of Lesch-Nyhan syndrome, a rare genetic disease that causes a very high level of uric acid in the blood.
• If you have or have had a thyroid problem.
• If you have an allergic reaction to Gautivide, stop using the medicine. Symptoms of an allergic reaction that may occur include severe effects (bullae, pitting, itching, rash that crusts).
• Swelling in the extremities or face.
• breathing difficulties.
• Fever with swollen lymph nodes.
• Also, a serious life-threatening allergic reaction may occur that leads to heart attack and cessation of blood circulation. Your doctor decides to completely stop using Gautvid. A few reports of a life-threatening allergic rash (Stevens-Johnson syndrome) with the use of Furic, start with the appearance of red spots on the skin or the appearance of Circular spots with blisters in the middle of the leg. Ulcers in the mouth, throat, nose, genitals and lining of the eyelid (swelling and redness of the eye) may also occur. The rash may increase and spread ulcers or skin blisters. If you develop Stevens-Johnson syndrome while using febuxostat, you should not re-use Gautvid in any other circumstances. anyway
• If you develop a rash or any of these skin symptoms, consult your doctor immediately and tell him that you are using this medicine.
• If you have a sudden attack of gout (sudden sharp pain, weakness, redness, heat and swelling in the joints), wait until the attack subsides before using Gattifed.
• In some people, gout attacks may increase when they start using certain medications that control the level of uric acid. Not all people have a flare-up or increase in symptoms, but symptoms can also increase with the use of Gautivide, especially in the first weeks or months of treatment. , It is important that you continue to use Gautivid even if you experience an increase in symptoms, as Gautvid still works to reduce the uric acid level with time, the attacks of gout will decrease and will be less painful with the continued use of Gautvid every day.
• Sometimes your doctor will prescribe other medications, if needed, to help prevent or treat symptoms of seizures (such as joint pain and swelling).
• Patients with high levels of urates (such as patients undergoing chemotherapy to treat cancer), treatment with urea-reducing drugs may lead to the accumulation of xanthine in the urinary tract, with the possibility of stones, although this has not been observed in patients who are being treated with Gautivide for tumor lysis syndrome
• Your doctor may order a blood test to make sure your liver is working normally.

The effect of Gautivide with other medicines:

Consult your doctor or pharmacist if you are taking, have recently taken, or could take any other medicines, including medicines obtained without a prescription.

It is especially important to consult a doctor or pharmacist if you are taking medicines containing any of the following substances because they may interact with Gautivide and the doctor needs to take necessary precautions:

• mercaptopurine (used to treat cancer).
• Azathioprine (used to reduce immune response).
• Theophylline (used to treat asthma), as there are no adequate studies when theophylline is used with febuxostat.

Gautivated during pregnancy and lactation:

Due to the lack of sufficient information for the use of this preparation during pregnancy, or if it is transmitted through breast milk, it is best as a precautionary measure, not to use this medicine during pregnancy and breastfeeding except after consulting the attending physician.

Gautivated with driving and using machines:

You should be aware that you may experience dizziness, drowsiness, blurred vision, and numbness or tingling sensations during the course of treatment and you should not drive or operate machinery in the event of these symptoms.

Possible side effects of Gautivide:

Like all medicines, Gautivide can cause side effects, although not everyone gets them.

Call your doctor at once or go to the nearest emergency department if you experience any of the following rare side effects (may affect up to 1 in 1,000 people):

Severe allergic reactions may occur: hypersensitivity reaction to the drug, a potentially life-threatening rash characterized by the formation of blisters, shedding of the skin and internal surfaces of the body cavity such as the mouth and genitals, painful ulcers of the mouth and/or genitals, accompanied by fever, inflammation Throat and tiredness (Stevens-Johnson syndrome/toxic epidermal necrolysis), or enlarged lymph nodes, hepatomegaly, hepatitis (may lead to cirrhosis), high level of white blood cells in the blood (drug interaction with white blood cells), generalized rash.

Common side effects (may affect 1 in 10 people):

• Difference in liver function analysis.
• Diarrhea.
• a headache.
• Simple rash.
• nausea.
• An increase in gout symptoms.
• Localized swelling due to fluid retention in body tissues (ascites)
• Uncommon side effects (may affect 1 in 100 people):
• decreased appetite;
• A change in the level of sugar in the blood (diabetes).
• Excessive feeling of thirst.
• An increase in the proportion of fats in the blood.
• Increase in weight.
• Loss of sex drive.
• difficulty sleeping, drowsiness;
• Dizziness.
• numbness, tingling;
• Loss or change of sensation (hypoesthesia, hemiparesis, or dysesthesia).
• Change or decrease in the sense of taste (loss of smell).
• Heart defect, irregular or rapid heartbeat, heart palpitations.
• Facial glow or sophistication.
• increased blood pressure;
• Bleeding (seen in patients taking chemotherapy due to blood disorders).
• Itch.
• Shortness of breath.
• Chest pain or discomfort.
• Inflammation of the nasal passage and/or throat (upper respiratory tract infection).
• Bronchitis.
• Dry mouth.
• Stomach pain/discomfort or flatulence, acidity, indigestion.
• Constipation.
• An increase in the number of stools.
• vomiting.
• colic.
• itching, blisters, dermatitis, skin discoloration, small red or crimson spots on the skin, small flat red spots on the skin, a flat red area on the skin covered with small bumps, rash, redness in places and spots, other types of skin conditions.
• Muscle spasm, muscle weakness, muscle/joint pain, synovitis or arthritis (inflammation of the joints often accompanied by pain, swelling and/or roughness) pain in the extremities, back pain, muscle cramping.
• The presence of blood in the urine, abnormal urination, abnormalities in urine tests (increase in the proportion of protein in the urine), a decrease in the ability of the kidneys to function abnormally.
• Tiredness, pain in the chest, a feeling of discomfort in the chest.
• Gallstones in the gallbladder or in the bile ducts (common bile duct stones).
• An increase in the thyroid stimulating hormone (TSH) in the blood.
• A change in the chemistry of the mouth or in the blood cells or platelets (imbalance in the results of the blood test)
• Kidney stones.
• Difficulty having an erection.

Rare side effects (may affect up to 1 in 1,000 people):

• Muscle damage is a rare and serious condition that may cause muscle problems, especially if you feel unwell or have a high temperature at the same time. This may be due to abnormal muscle damage. Call your doctor at once if you experience pain, weakness or muscle weakness.
• Acute inflammation of the deeper layers of the skin, especially around the lesion, eyes, reproductive system, hands, feet, or tongue, with possible sudden difficulty in breathing, high temperature with measles-like rash, enlarged lymph nodes, enlarged liver, hepatitis ( May lead to kidney damage), an increase in the number of white blood cells in the blood (leukocytes with or without eosinophils).
• Redness of the skin (dermatitis), rashes of various types (itching, white spots with blisters, blisters with pus, shedding of the skin, measles-like rash), widespread dermatitis, necrosis, blistering of the skin and mucous membranes, leading to peeling and possible Sepsis (Stevens-Johnson Syndrome / toxic epidermal necrolysis).
• nervous.
• feeling thirsty
• ringing in the ear
• blurred vision, different vision
• Hair loss.
• Oral ulcer.
• Pancreatitis – common symptoms are abdominal pain, nausea and vomiting).
• increase in sweating;
• Decreased weight, increased appetite, uncontrolled loss of appetite.
• Muscle and/or joint stiffness.
• An abnormally low number of blood cells (white or red blood cells or platelets).
• Urgent need to urinate.
• Change or decrease in the amount of urine due to inflammation of the kidneys.
• Lever Inflammation.
• Yellowing of the skin (yellowishness).
• If you get any side effects, talk to your doctor or pharmacist. This includes any other side effects not mentioned in this thread.

What is the price of the medicine Gautivid?

• Gautivide 40 mg Tablets (30 Tablets), At a price of 51 Egyptian pounds.
• Gautivide 80 mg Tablets (30 Tablets), At a price of 69 Egyptian pounds.
• Gautivide 120 mg Tablets (30 Tablets), At a price of 90 Egyptian pounds.

Gautivide alternatives:

Medicines containing the same active substance and the same concentrations.

Data sources & Price & References

Egyptian drug index
Last updated on: May 30, 2022

Goutifade leaflet
Last updated on: May 30, 2022

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