دواء باروكسيتين Paroxetine مضاد للإكتئاب

Price, dosage, and instructions for using Paroxetine to treat depression.

What is the drug Paroxetine?

Paroxetine is an antidepressant medicine that belongs to the group of selective serotonin reuptake inhibitors (SSRIs).

Paroxetine Ingredients:

Active ingredient: paroxetine (paroxetine).

Concentrations and dosage form:

• Paroxetine is an extended-release tablet, in a concentration (12.50mg – 25mg – 37.50mg).
• Paroxetine (20mg) film-coated tablets.

What are the indications for the use of the drug Paroxetine?

Paroxetine is a medicine prescribed to treat the following conditions:

• Major depressive disorder.
• panic states;
• cases of social anxiety.
• Premenstrual depressive disorder.

Paroxetine Dosage and Instructions:

• Take the medicine exactly as your doctor has prescribed. Your doctor may need to change your dose of the medicine until it reaches the right dose for you.
• Paroxetine is used in the morning with or without food.
• The usual dose of paroxetine in the treatment of major depressive disorder is the initial dose of 25 mg once daily, and the dose can be increased according to the doctor’s instructions to 37.5 mg daily, while the maximum dose can be 62.50 mg daily.
• The usual dose in the treatment of panic conditions is the starting dose of 12.50 mg once daily and may be increased according to the doctor’s instructions to a maximum dose of 75 mg.
• The usual dose in the treatment of social anxiety cases is the starting dose of 12.50 mg per day, and it can be increased according to the doctor’s instructions to 37.5 mg per day.
• The usual dose in the treatment of premenstrual depressive disorder is the initial dose of 12.50 mg once daily and may be increased according to the physician’s instructions to 25 mg daily.
• In cases of the elderly and patients with renal and hepatic impairment, the initial dose is 12.50 mg once daily, and it can be increased according to the doctor’s instructions, provided that the dose does not exceed 50 mg daily.
• The medicine should not be chewed or broken.
• If you forget to take a dose: Take the forgotten dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not double the dose of the medicine at the same time.
• If you take an overdose of Paroxetine, contact your doctor or poison control center immediately or seek emergency treatment.
• Do not stop taking the medicine suddenly without consulting your doctor (unless you have symptoms of a severe allergic reaction). If you want to stop taking the medicine, your doctor can tell you how to stop taking it safely.

Precautions and warnings for the use of Paroxetine:

Before taking this medicine, you should tell your doctor if you suffer from any of the following problems:

• You have liver problems.
• You have kidney problems.
• You have heart problems.
  If you suffer or have suffered from epileptic fits or convulsions.
• You have bipolar disorder or mania.
• If you suffer from low levels of sodium in the blood.
• You have high blood pressure.
• You have or have had bleeding problems.
• You have glaucoma (high pressure in the eyes).
• Tell your doctor all the medicines you take, including prescription or over-the-counter medicines, vitamins, and herbal supplements. Paroxetine and other medicines may interact with each other, may not work properly, or can cause serious side effects, your doctor or pharmacist can tell you If it is safe for you to take paroxetine with other medicines you are taking, do not start or stop taking any medicine while taking paroxetine without first talking to your doctor. العدسة نيوز

Warnings after taking Paroxetine:

• Do not stop taking your medicine without talking to your doctor first. Stopping taking the medicine too quickly can cause some symptoms, including: anxiety, irritability, high or low mood, feeling restless, or changes in sleeping habits, headache, sweating, nausea, or dizziness, feeling like an electric shock, shaking, or disorientation.
• This medicine can make you sleepy or affect your ability to make decisions, think clearly or respond quickly. You should not drive, operate heavy machinery, or do other dangerous activities until you know how the medicine affects you.
• Do not drink alcoholic beverages while taking this medicine.
• Antidepressants such as (paroxetine) increase the risk of suicidal ideation in children, adolescents and young adults, according to short-term studies of severe depression and other mental illnesses.
• Infants born to mothers who took an SSRI after the 20th week of gestation were 6 times more likely to have persistent pulmonary hypertension (PPHN) than infants born to mothers who did not take an antidepressant during pregnancy.
• The risk of major congenital malformations, especially cardiac malformations, in an infant born to women taking paroxetine during the first trimester of pregnancy may be nearly twice as high as for women taking other antidepressants.
• A life-threatening condition called serotonin syndrome can occur when a drug called selective serotonin reuptake inhibitors (SSRIs), such as paroxetine, is used in combination with a medication used to treat migraines known as a triptan. A recent change in treatment regimen including: (agitation, ataxia, profuse sweating, diarrhea, fever, hyperreflexia, myoclonus, tremors, changes in mental status.

Paroxetine during pregnancy and lactation:

• If you are pregnant, there is a possibility of pregnancy, or planning to become pregnant, there is a possibility that the drug could harm the fetus and include an increased risk of congenital malformations, especially heart defects, other risks that can include serious conditions characterized by not enough oxygen in the child’s blood, your child can also To experience other symptoms shortly after birth, premature births have also been reported in some women who took paroxetine during pregnancy.
• If you are breast-feeding, paroxetine passes into breast milk, you should talk to your doctor about the best way to feed your baby while you are taking this medicine.

Interaction of paroxetine with other medicines:

Before taking paroxetine, tell your doctor if you are taking any other medicines, especially the following:

• Triptans used to treat migraine headaches.
• Other antidepressants (selective serotonin reuptake inhibitors, lithium tricyclic antidepressants) or antipsychotics.
• Medicines that affect serotonin, such as lithium, tramadol, tryptophan, or St. John’s wort.
• Certain medicines to treat an irregular heartbeat.
• Certain medicines to treat schizophrenia.
• Certain medicines to treat HIV infection.
• Certain medications that affect the blood, such as warfarin, aspirin, and ibuprofen.
• Certain medicines to treat epilepsy.
• Anomoxetine.
• cimetidine;
• fentanyl;
• metoprolol
• pimozide;
• Bruxilidine.
• tamoxifen;
• If you are taking paroxetine, do not take medicines that contain paroxetine, including paroxetine and Pexeva (paroxetine methylate).

Medicines not to be taken with paroxetine:

• Do not take paroxetine if you are taking an MAO inhibitor. Ask your doctor or pharmacist if you are not sure if you are taking an MAO inhibitor, including the antibiotic linezolid.
• If you are taking Milaril (thioridazine), do not take Milaril together with paroxetine because this can lead to serious heart rhythm problems or sudden death.
• Do not take paroxetine if you are taking the antipsychotic pimozide (Orap), as this can cause serious heart problems.

Contraindications to the use of Paroxetine:

• Do not take paroxetine if you are allergic to paroxetine or any of the other ingredients in this medication.
• Do not take paroxetine if you are taking an MAO inhibitor. Ask your doctor or pharmacist if you are not sure if you are taking an MAO inhibitor, including the antibiotic linezolid.
• Do not take an MAOI within two weeks of stopping paroxetine unless your doctor tells you to.
• Do not start taking a medication if you stop taking an MAOI in two weeks unless your doctor tells you to.
• People who take paroxetine at the same time as monoamine oxidase inhibitors can have serious or life-threatening side effects, seek medical attention immediately if you experience any of the following symptoms: (high fever – uncontrollable muscle spasms) muscle stiffness, rapid changes in heart rate or blood pressure, confusion, loss of consciousness.
• If you are taking Milaril (thioridazine), do not take Milaril together with paroxetine because this can lead to serious heart rhythm problems or sudden death.
• Do not take paroxetine if you are taking the antipsychotic pimozide (Orap), as this can cause serious heart problems.

Possible side effects of paroxetine:

Like all medicines, this medicine can cause side effects, but not everyone gets it.

Possible side effects of paroxetine include:

• nausea;
• drowsiness;
• Feeling anxious or having trouble sleeping.
• Problems in marital relations.
• sweating;
• Vibration.
• constipation;
• yawn;
• Blurred vision.
• Diarrhea.
• dry mouth
• lack of appetite
• general weakness.

Paroxetine and other antidepressants in general can cause more serious side effects, including:

(1) Risk of suicidal thoughts or actions:

• Paroxetine and other antidepressants may increase suicidal thoughts or actions in some children, adolescents, and young adults during the first few months of treatment or when the dose is changed.
• Depression or other serious mental illnesses are the main causes of suicidal thoughts and actions.
• You should note these changes or contact your doctor immediately if you notice the following: (new or sudden changes in mood, behavior, actions, thoughts, or feelings, especially if they are severe), you should pay close attention to these changes when you start taking this medicine or when changing the dose, Make follow-up visits to your doctor regularly and you should contact your doctor between visits if you are concerned about these symptoms.

Call your doctor right away if you experience any of the following symptoms if the symptoms are new, worse, or cause you concern:

• Suicidal tendency.
• Acting in a dangerous rush.
• Acting nervous or violent.
• Thoughts of suicide or death.
• New or bad anxiety or panic attacks.
• Feeling agitated, restless, angry or irritable quickly.
• sleep problems
• Thoughts of suicide or death.
• New or bad depression.
• Increased activity and talking more than usual.
• Other unusual changes in behavior and mood.

(ii) Serotonin Syndrome or Malignant Neuroleptic Syndrome-like Reactions:

• Agitation, hallucinations, coma, or other changes in mental status.
• Problems coping or muscle twitching (overactive reflexes).
• Rapid heartbeat, high or low blood pressure.
• Sweating or fever.
• Nausea, vomiting, or diarrhea.
• Muscle stiffness.

(3) Visual problems:

• Eye pain.
• Vision changes.
• Swelling or redness around the eye.

Only some people are prone to these problems. You may want to have an eye exam to see if you’re at risk and receive preventive treatment if it’s serious.

(4) Severe allergic reactions:

• breathing problems
• Swelling of the face, tongue, eyes or mouth.
• Skin rash, itchy bumps (urticaria) or skin blisters, these symptoms appear alone or accompanied by fever or joint pain.

(5) Abnormal Bleeding:

Paroxetine and other antidepressants can increase the risk of bleeding or bruising especially if you are taking the blood thinner warfarin (Coumadin, Juntoven), nonsteroidal anti-inflammatory drugs (such as ibuprofen or naproxen) or aspirin.

(6) Epileptic fits or convulsions.

(7) Manic episodes:

• Significant increase in energy.
• Severe problems sleeping.
• Conflicting ideas.
  impulsive behaviours.
• Unusually huge ideas.
• Extreme happiness or excitement. العدسة نيوز
• Talking a lot or faster than usual.

(8) Change in appetite or weight:

The height and weight of children and adolescents should be monitored during treatment.

(9) Low levels of salts (sodium) in the blood:

Older people may be more susceptible to this, and symptoms include: (headache – weakness or feeling unstable – confusion – problems concentrating or thinking, or memory problems).

Tell your doctor if you have side effects that make you feel uncomfortable or that do not go away. These are not all possible side effects of the medicine.

What is the price of the drug Paroxetine?

• Paroxetine 20 mg film-coated tablets (30 tabs) 3 strips, At a price of 66 Egyptian pounds.
• Paroxetine extended-release 12.50 mg (30 tablets) 3 strips, At a price of 54 Egyptian pounds.
• Paroxetine Extended Release 25 mg (30 Tablets) 3 strips, At a price of 69 Egyptian pounds.
• Paroxetine extended-release 37.50 mg (30 tablets) 3 strips, At a price of 81 Egyptian pounds.

How is the medicine stored?

Store this medicine at room temperature or below 30°C.

Data sources & Price & References

Egyptian drug index
Last updated on: July 14, 2022

Paroxetine leaflet
Last updated on: July 14, 2022

The pharmacy treatment website is not responsible for taking the “Paroxetine” medication without consulting the doctor or the pharmacist. The information about the medication was written by a “specialized pharmacist” and reviewed from the leaflet attached to the company inside the medication box itself.

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